The skin is the largest organ of the body and its outermost layer, the epidermis, is the first barrier of defense against external aggressions and water loss.

It is a complex system comprising epithelial cells, a lipid matrix, the immune system and the microbiome or set of microorganisms that live on our skin and whose presence is essential for its health.

The balance of this entire system is important for the maintenance of skin barrier integrity and overall health.